Use of cultured epithelial cells, including keratinocytes, for the detection of antinuclear antibodies.

نویسندگان

  • I Leigh
  • F Wojnarowska
  • S Burge
  • B Bhogal
  • T Zhu
چکیده

The use of cultured human epithelial cells as a substrate for the detection of antinuclear antibodies (ANAs) improves the sensitivity of detection above the standard substrates used. Standard antisera have been screened against a series of epithelial cell lines, including keratinocytes. Selected cells have then been used to detect ANAs in 78 patients with discoid lupus erythematosus.

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عنوان ژورنال:
  • Annals of the rheumatic diseases

دوره 46 12  شماره 

صفحات  -

تاریخ انتشار 1987